Optimum design of a palmitoyl arginine surfactant from arginine in mix solvent hexane-isopropanol

The added value of amino acids and palm oil derivatives as raw materials for amide surfactants has developed recently. Therefore, amide formation by the amino acid and arginine was investigated as a mix of solvent ratio, catalyst amount, and substrate ratio. Response Surface Methodology with Central Composite Design and twenty combination treatments synthesized this surfactant palmitoyl arginine. The results generally show that the highest conversion will be produced at the maximum selection of solvent ratio, catalyst amount, and substrate ratio variables. Only the interaction between the mixed solvent ratio and the substrate ratio has a significant effect on the interaction effect. However, the square of the interaction of the three variables has a very significant effect on the conversion of palmitic acid.