The Dedifferentiated Liposarcoma Arising from Jejunal Mesentery ∼Probably Multicentric Origin

We report a case of multicentric dedifferentiated liposarcoma. A 47-year-old woman seen for lower abdominal pain and fever was found on palpation to have slight overall abdominal tenderness with slight rebound tenderness and guarding. Laboratory data showed leucocytosis (WBC 11,800 /mm3) and inflammation (CRP 20.6 mg/dl) and plain abdominal computed tomography (CT) showed tumors in the upper and lower right abdominal cavity. We conducted laparotomy, finding multiple mesenteric lipoma or liposarcoma from abdominal enhanced CT and Magnetic resonance imaging (MRI), etc. The pedunculated pelvic tumor was twisted and caused ischemia and severe inflammation. Finding radical resection to be unfeasible, we resected as many tumors as possible. Residual tumors slowly increased and abdominal symptoms became marked, necessitating three times of progressive tumor-reductive resection and laparotomy over 3 years 6 months.