A Case of Signet Ring Cell Carcinoma of the Gallbladder

We experienced a case of signet ring cell carcinoma of the gallbladder which is rare as primary tumor of the gallbladder. The patient was a 70-year-old male. He had an operation of laparoscopic cholecystectomy with the diagnosis of cholecystolithiasis at the Hokkaido hno Hospital. A slightly elevated (IIa) whitish lesion (8×7mm) was detected on the mucosal surface of the abdominal side of the resected gallbladder body. Pathological diagnosis was signet ring cell carcinoma, slightly infiltrating into subserosa, and no other histological structure of malignant cells were detected. Lymphatic or venous infiltration was not detected. He was admitted to Surgical Oncology Hokkaido University for he treatment. CT denied residual cancer or lymphatic metastasis, but we decided to add operation. The operation method was cuneiform resection of the liver bed, and resection of the bile duct and D2 lymph node. He had no postoperative complication and the pathological examination indicated no residual malignant cell. He is alive without recurrence 34 months after the operation. Signet ring cells of the gallbladder tend to coexist with other histological forms of malignant cells, but in this case the signet the bile duct and D2 lymph node. He had no postoperative complication and the pathological examination indicated no residual malignant cell. He is alive without recurrence 34 months after the operation. Signet ring cells of the gallbladder tend to coexist with other histological forms of malignant cells, but in this case the signet well as in the stomach.