A Resected Case of Primary Hepatic Malignant Lymphoma

A 37-year-old man with upper abdominal pain and high fever originally diagnosed with inflammatory hepatic pseudotumor elsewhere was admitted when the tumor gradually grew during follow-up. Abdominal CT showed a slightly enhanced, heterogeneous mass occupying the left hepatic lobe, and an another tumor 2.5cm in diameter in liver segment VIII. Although accurate diagnosis was difficult, malignant disease was highly suspected both clinically and radiographically, necessitating hepatic lobectomy and partial liver resection. Histopathological findings showed diffuse large B cell non-Hodgkin lymphoma. Whole-body CT, Ga scintigraphy, and bone marrow biopsy did not demonstrate other lesions and the definitive diagnosis was primary hepatic malignant lymphoma. CHOP therapy postoperatively for 6 courses as adjuvant chemotherapy resulted in no recurrent lesions observed 18 months after surgery. It seems effective to perform surgical resection followed by adjuvant chemotherapy in the case of primary hepatic lymphoma without extrahepatic disease.