A Case of Early Depressed Duodenal Cancer of the Second Portion

A 72-year-old man was admitted to our hospital with a chief complaint of tarry stools. Gastrointestinal endoscopy revealed an irregular, depressed lesion in the anterior wall of the second portion of the duodenum. Histological examination of the biopsy specimen revealed adenocarcinoma. Pancreatoduodenectomy was performed. The resected specimen contained a 1.6×1.0 cm irregular, depressed lesion, away from the papilla of Vater. The histological diagnosis was moderately-differentiated tubular adenocarcinoma, with cancer cells confined within the submucosal layer of the duodenum, and no lymph node metastasis or vascular invasion. This case appears to be the 14th case of early, depressed duodenal cancer ever reported in Japan.