A Case Report of Localized Gastric Amyloidosis with Calcification

A 63-year-old man was referred to our hospital suffering from a chronic subdural hematoma. The plain X-ray of the abdomen taken on admission showed abnormal calcification in the upper left quadrant. Radiological and endoscopic examination revealed a tumor at the fundus which was suggestive of malignancy, however, the biopsyyielded normal findings. Microscopic examination of the resected specimen showed an amyloid deposit in the gastric wall, especially in the submucosal layer. The amyloid material was found to be AL type, and there were some calcifications and a few ossifications among the amyloid deposits. Further histological evaluation of the liver, rectum and bone marrow showed no deposits, and the urine was negative for Bence Jones protein. Therefore the condition was diagnosed as localized gastric amyloidosis with calcification. According to our review localized gastric amyloidosis have been reported only 20 cases and there are no reports about associated calcification.