A Case of Multiple Pancreatic Serous Cystic Neoplasm Accompanied by Main Pancreatic Duct Stenosis

A 66-year-old woman was referred to our hospital after CT incidentally revealed a tumor in the pancreatic head. Contrast-enhanced CT showed a multifocal and microcystic tumor of around 45 mm in the pancreatic head that was enhanced in the early phase. This imaging also showed a tumor of around 10 mm with poor contrast enhancement in the pancreatic body that was accompanied by pancreatic duct dilation. Pancreatic serous cystadenoma (SCA) in the pancreatic head and carcinoma of the pancreatic body were diagnosed, and total pancreatectomy was performed. Histopathological examination showed that both tumors were SCA. SCA is a benign tumor that generally occurs as a single lesion and is not associated with pancreatic duct stenosis. Multiple SCA is rare. SCA larger than 4 cm has been found to be more likely to cause subjective symptoms and is suitable for surgery. A tumor in the pancreatic body accompanied by stenosis of the main pancreatic duct may also be pancreatic carcinoma. For these reasons, we selected total pancreatectomy in our case.