High risk HPV rate of detection and the genotyping study used remainder specimen of BD SurePathTM method

Objectives : We investigated the detection rate and genotypes of HR-HPV in endocervical cytology specimens to examine the importance of HR-HPV detection and HR-HPV genotyping in cervical cancer screening.Study Design : The study population was composed of women being followed up by periodic checkups for SIL and those undergoing secondary health examinations ; the women from both subgroups were aged ≥20 years. Cases with ASC-US or more severe abnormalities on BD SurePathTM were subjected to genotyping for HR-HPV and underwent cervical biopsy.Results : Of the 134 subjects examined, 108 (80.6%) were found to be positive for HR-HPV. There were 86 subjects in whom the HR-HPV types could be identified, with types 16, 52 and 58 accounting for ≥10% of cases each, and for 48.8% (42/86) overall. Of the subjects with CIN 2 or more severe lesions, 82.6% (38/46) were found to be positive for any of the HR-HPV types 16, 52 and 58, with this percentage increasing to 95.7% (44/46) when types 18, 31 and 33 were also included. The HR-HPV positive rates in cases with CIN 2 or more and