Cytological Findings of Testicular Tumor, especially Seminoma and Embryonal Carcinoma

In cases of testicular tumor, seminoma and embryonal carcinoma were seen more frequently than othertypes.But seminoma and embryonal carcinoma differed significantly in clinical findings. Specimens forthe cytological study were obtained by imprintingand aspiration of tumorous testis or metastatic lymphnodes from 7 patients with seminoma and 4 patients with embryonal carcinoma. Cytological findings onseminoma and embryonal carcinoma are as follows: Seminoma: Tumor cells are monotonous and noncohesive. The cells are polygonal, and their cytoplasmic rims are distinct. Nuclei are oval or round, with thin and smooth rims as well as delicate chromatin networks. Prominent round nucleoli are locatedin the center. Cytoplasm is clear and stained lightgreen in perinuclear region by the Pap. method, whileit either is homogeneously light blue or shows marginal vacuolization by the M-G method. Embryonal Carcinoma: Tumor cells are in closeclumps. Shapes of cells are irregular, they are fibrous, spindleshaped or tadpoleshaped at times. The cytoplasmic rims are indistinct.Nuclei are irregular in shape or oval with thin rims and fine granular chromatins. Nucleoli are irregularly shaped or round.Cytoplasms are foamy and stained light green by the Pap. method, and light blue or amphophilic by the M-Gmethod. They are in many cases vacuolated.