Analytical Techniques in Exploring the Persistent Global PFAS Problem

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals with unique properties. They are used in a wide range of different industries because they repel water and oil, and they are heat-resistant. However, PFAS contamination has become a widespread global concern because of their ubiquitous occurrence, persistence in the environment and living organisms, and potential health risks. Governments around the world are continuously introducing and updating regulatory limits for PFAS in drinking water, other types of water, biota, and, most recently, food. Analyzing such a wide range of sample types for PFAS requires high sensitivity and selectivity, typically provided by methods based on advanced liquid chromatography–tandem quadrupole mass spectrometry (LC–MS/MS) instrumentation. However, one critical aspect to sampling and analyzing PFAS accurately is to avoid PFAS contamination during these processes. This paper emphasizes the significance of robust and reliable PFAS analysis to support efforts to mitigate the global PFAS crisis. Collaboration, research, and advanced analytical solutions are essential to safeguard food, water, and the environment, thusly reducing the impact of PFAS on public health and the environment.