Anionic Surfactants as Detergents for Scalp and Hair

The influences of six representative surfactants on hair and the scalp were investigated under various conditions such as : irritation, protein denaturation, sorption onto commercial hide powder or keratin powder, change in turnover time of the stratum corneum, dandruff and disintegration of the cuticle. 1. Influence of surfactants on scalp. Although the cumulative irritation test, 48-hour closed patch test, and immersion test were performed to assess the irritating effects of surfactants, the results did not agree with each other. The immersion test, which makes essentially the same use of surfactants, gave results in close agreement with those for sorption of sufactants or protein denaturation by surfactants. Amounts of surfactants sorbed by hide powder. Irritation score of immersion test : r=0.671. Amounts of surfactants sorbed by keratin powder. Irritation score of immersion test : r=0.930. Per cent denaturation of OVA by surfactants. Irritation score of immersion test : r=0.880. Turnover times of the stratum corneum due to the surfactants were found to follow the order, AMT≤AGS≤L-Soap≤AP