Studies of Improvement on the Preparation of Disinfectants: Development of the Open-top Screw-cap

At Kyoto University Hospital, disinfectants are prepared by injecting the concentrated disinfectant agents directly into 500 ml bottles of sterile purified water, which are equipped with a new open-top screw-cap. When our new disinfectant preparation method using the open-top screw-cap was compared with that using the regular screw-cap, the method was found to be much more useful from a variety of perspectives, such as hermetic sealing, sterilizing, handling and treatment time. In addition, the open-top screw-cap wrapped with a plastic cover seat could easily prevent contamination by a range of bacteria during disinfectant preparation which was considered to be of value in the preparation of disinfectants in hospital pharmacy.