Prospective cohort study of the feasibility and yield of household child tuberculosis contact screening in Uganda

SETTING: Screening and isoniazid preventive therapy (IPT) of child contacts of tuberculosis (TB) patients is poorly implemented in resource-limited countries, in part due to difficulties in TB diagnosis in children.OBJECTIVE: To assess the feasibility and yield of hospital-based screening and IPT in...

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Veröffentlicht in:	The international journal of tuberculosis and lung disease 2017-08, Vol.21 (8), p.862-868
Hauptverfasser:	Bonnet, M., Kyakwera, C., Kyomugasho, N., Atwine, D., Mugabe, F., Nansumba, M., II, Y. Boum, Mwanga-Amumpaire, J., Kiwanuka, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Age Algorithms Antitubercular Agents - administration & dosage Child, Preschool Childhood Tuberculosis Children Children & youth Cohort analysis Cohort Studies Contact Tracing - methods Cough Cough - epidemiology Cough - etiology Feasibility Studies Female HIV HIV Infections - epidemiology Human immunodeficiency virus Humans Infant Isoniazid Isoniazid - administration & dosage Latent Tuberculosis - diagnosis Latent Tuberculosis - prevention & control Male Mass Screening - methods Predictive Value of Tests Prospective Studies Screening Sensitivity and Specificity Symptom-Based Screening Tuberculosis Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - prevention & control Uganda Viruses
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Beschreibung
Zusammenfassung:	SETTING: Screening and isoniazid preventive therapy (IPT) of child contacts of tuberculosis (TB) patients is poorly implemented in resource-limited countries, in part due to difficulties in TB diagnosis in children.OBJECTIVE: To assess the feasibility and yield of hospital-based screening and IPT in Uganda, and to evaluate the utility of symptom-based screening.DESIGN: Household child (age
ISSN:	1027-3719 1815-7920
DOI:	10.5588/ijtld.16.0889