Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Aromatic a-Bromoketones, Sodium Azide and Terminal Acetylenes via Cu/Cu(OTf)2-catalyzed Click Reaction under Microwave Irradiation

Reaction of aromatic a-bromoketones, sodium azide and aromatic or aliphatic terminal acetylenes in the presence of Cu/Cu(OTf) following the classical method (aqueous acetonitrile at room temperature) and under microwave irradiation (H O at 85 °C) leads to 1,4-disubstituted 1,2,3-triazoles as the fin...

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Veröffentlicht in:Zeitschrift für Naturforschung. B, A journal of chemical sciences A journal of chemical sciences, 2013-04, Vol.68 (4), p.391-396
Hauptverfasser: Fazeli, Azadeh, Oskooie, Hossein A., Beheshtiha, Yahya S., Heravi, Majid M., Moghaddam, Firouz Matloubi, Foroushani, Behzad Koushki
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container_title Zeitschrift für Naturforschung. B, A journal of chemical sciences
container_volume 68
creator Fazeli, Azadeh
Oskooie, Hossein A.
Beheshtiha, Yahya S.
Heravi, Majid M.
Moghaddam, Firouz Matloubi
Foroushani, Behzad Koushki
description Reaction of aromatic a-bromoketones, sodium azide and aromatic or aliphatic terminal acetylenes in the presence of Cu/Cu(OTf) following the classical method (aqueous acetonitrile at room temperature) and under microwave irradiation (H O at 85 °C) leads to 1,4-disubstituted 1,2,3-triazoles as the final products after simple filtration.
doi_str_mv 10.5560/znb.2013-3043
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identifier ISSN: 0932-0776
ispartof Zeitschrift für Naturforschung. B, A journal of chemical sciences, 2013-04, Vol.68 (4), p.391-396
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1865-7117
language eng
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source Alma/SFX Local Collection
subjects 1,4-Disubstituted 1,2,3-Triazoles
Click Reaction
Copper/Copper Triflate
Cycloaddition
Microwave Irradiation
Three-Component Reaction
α-Bromoketones
title Synthesis of 1,4-Disubstituted 1,2,3-Triazoles from Aromatic a-Bromoketones, Sodium Azide and Terminal Acetylenes via Cu/Cu(OTf)2-catalyzed Click Reaction under Microwave Irradiation
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