Granular Cell Astrocytoma

Granular cell astrocytoma (GCA) is a rare glial neoplasm composed of abundant granular cytoplasm gives immunoreactivity for GFAP and S100 stains. We report a case of GCA in a 64 years old male presented with history of fits, right sided weakness and loss of consciousness. The microscopy showed sheet...

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Veröffentlicht in:Journal of Ayub Medical College, Abbottabad Abbottabad, 2023-02, Vol.35 (1), p.158-160
Hauptverfasser: Batool, Ayma, Bashir, Azra, Javeed, Saira, Zaman, Samina, Chughtai, Akhtar Sohail
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Sprache:eng
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Zusammenfassung:Granular cell astrocytoma (GCA) is a rare glial neoplasm composed of abundant granular cytoplasm gives immunoreactivity for GFAP and S100 stains. We report a case of GCA in a 64 years old male presented with history of fits, right sided weakness and loss of consciousness. The microscopy showed sheets of large cells with abundant eosinophilic granular cytoplasm. No high-grade features were seen. Its differential diagnosis includes most of the benign histiocytic conditions. Granular cell astrocytoma has an aggressive clinical course and its survival rate is less than 1 year. That's why early correct diagnosis is very essential.
ISSN:1025-9589
1819-2718
DOI:10.55519/JAMC-01-10493