In Process Quality Control Factors Affecting Potency of Fowl Cholera Vaccine

Fowl cholera (FC) is one of the respiratory syndromes of commercial layer, breeder and broiler farms in Pakistan. The disease is mainly controlled by vaccination. In the present study, effect of "in process quality control" factors such as amount of immunogen, chemical nature of adjuvant,...

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Veröffentlicht in:International journal of biology 2019-02, Vol.11 (2), p.23
Hauptverfasser: Mehmood, Muhammad Danish, Qazi, Mahmood Hussian, Muhammad, Khushi, Amin, Faisal, Anwar, Huma, Ismail, Muhammad
Format: Artikel
Sprache:eng
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Zusammenfassung:Fowl cholera (FC) is one of the respiratory syndromes of commercial layer, breeder and broiler farms in Pakistan. The disease is mainly controlled by vaccination. In the present study, effect of "in process quality control" factors such as amount of immunogen, chemical nature of adjuvant, fractions of bacterial culture and its storage on potency of the vaccine was investigated. Immunogen amount (1011CFU/ml) induced serum anti-Pasteurella multocida ELISA (anti-PM-ELISA) antibody titer in the vaccinated birds on 32 days post vaccination that was significantly higher (P
ISSN:1916-9671
1916-968X
DOI:10.5539/ijb.v11n2p23