SYNTHESIS OF COBALT FERRITE NANOPARTICLES AND THEIR APPLICATIONS IN HYPERTHERMIA THERAPY

Co-ferrite nanoparticles have been prepared by wet chemical route using micelles. Two sets of particles with sizes of⁓100 nm and ⁓200 nm were obtained by varying the concentration of micelles. The morphological and crystallographicstudy of the particles was performed by scanning electron microscope (SEM) and x-ray diffractometer respectively. Tocheck the suitability of the co-ferrite nanoparticles in magnetic hyperthermia therapy, various magnetic measurementswere carried out in presence of AC and DC magnetic fields. To investigate the suitability of the particles in hyperthermiatherapy hysteresis loss of the particles under the application of AC magnetic field with various frequencies has beencarried out. The parabolic nature of power loss with the frequency of the applied AC field has been verified fromexperimental data. From various measurements, it appeared that the particles with an average size ~100 nm have betterefficiency in view of hyperthermia therapy. A large value of the specific absorption rate (SAR) was found from the achysteresis of the particles.