PREVALENCE OF ONCOGENIC VIRUSES IN TUMORS OF THE THYROID GLAND IN THE STATE OF AMAZONAS, NORTHERN BRAZIL: PRELIMINARY FINDINGS

INTRODUCTION: Thyroid cancer is the most prevalent type of endocrine cancer worldwide, being necessary to investigate possible associations with oncogenic viruses. OBJECTIVE: To evaluate the presence of viral infection in thyroid tissue fragments obtained surgically in a public hospital in Amazonas,...

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Veröffentlicht in:Revista Foco 2024-02, Vol.17 (2), p.e2641
Hauptverfasser: Do Nascimento, Emily Barbosa, Da Silva, Jessica Miguel Medeiros, De Souza, Jhonnatan Silva, Botelho, João Bosco Lopes, De Lima, Luiz Carlos, De Carvalho, Diego Monteiro, Martins, Valquíria do Carmo Alves, Ono, Lia Mizobe
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Sprache:eng
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Zusammenfassung:INTRODUCTION: Thyroid cancer is the most prevalent type of endocrine cancer worldwide, being necessary to investigate possible associations with oncogenic viruses. OBJECTIVE: To evaluate the presence of viral infection in thyroid tissue fragments obtained surgically in a public hospital in Amazonas, Brazil. METHODS: Observational, descriptive cross-sectional study of thyroid tumor surgical specimens examined for the presence of oncogenic viruses EBV and B19 by real-time PCR. RESULTS: Sixty samples were analyzed, of which 10 had EBV DNA and 13 B19 DNA. Pearson’ chi-square test and Fisher’s exact test for the association between viral presence and tumor histological type were not statistically significant for EBV (P-value = 0.6288) or B19 (P-value = 1.0). CONCLUSION: Partial results did not reveal a positive association between viral presence and histological type.
ISSN:1981-223X
1981-223X
DOI:10.54751/revistafoco.v17n2-023