RELATIONSHIP BETWEEN 25(OH) D LEVELS AND DYSBIOSIS IN CHILDREN - SYSTEMATIC REVIEW

Objective: We systematically analyzed the relationship between 25(OH)D serum levels and intestinal dysbiosis in children. Methods: The following databases were systematically searched: Pubmed, Embase, Lilacs, Scopus, Ebsco, and Cochrane. Two reviewers independently examined the studies, collected data, assessed the risk of bias, and ranked the levels of evidence for each outcome in the studies. The pre-specified parameters of interest were 25(OH)D serum levels; sex and intestinal dysbiosis. We only included data from peer-reviewed articles in our analyses. Results: In our primary analysis, there was a positive trend between serum 25(OH)D