Relationship between familial mediterranean fever and soluble receptor for advanced glycation end products

Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory disease worldwide and is characterized by recurrent fever and serositis. Serum soluble receptor for advanced glycation end products (sRAGE) is an isoform of RAGE and sRAGE acts as a trap receptor for ligands and blocks...

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Veröffentlicht in:Medicine science 2022, Vol.11 (3), p.1000
Hauptverfasser: Okuyucu, Muhammed, Kehribar, Demet
Format: Artikel
Sprache:eng
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Zusammenfassung:Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory disease worldwide and is characterized by recurrent fever and serositis. Serum soluble receptor for advanced glycation end products (sRAGE) is an isoform of RAGE and sRAGE acts as a trap receptor for ligands and blocks the RAGE–ligand axis. This study aimed to examine the change in sRAGE levels in FMF and to investigate its relationship with inflammation. This study included patients with FMF (n=20) and healthy controls (n=22). Morbidity status, sRAGE levels, demographic and laboratory data were recorded. Pregnant women, individuals aged
ISSN:2147-0634
2147-0634
DOI:10.5455/medscience.2022.03.049