Los virus como detonante oncogénico

Viruses are intracellular pathogens, which are replicated within a cell, using their own machinery to generate more viral particles. Viral replication can affect normal host cell genes, thereby modulating signaling pathways that control cell proliferation, differentiation, and death; genomic integri...

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Veröffentlicht in:Tequio (en línea) 2018-01, Vol.1 (2), p.57-67
Hauptverfasser: López-Martínez, Jael, Gabriel de la Torre, María del Pilar, Cruz Ochoa, Cristian, Martínez-Martínez, Lucía, Mayoral Chávez, Miguel Ángel
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container_issue 2
container_start_page 57
container_title Tequio (en línea)
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creator López-Martínez, Jael
Gabriel de la Torre, María del Pilar
Cruz Ochoa, Cristian
Martínez-Martínez, Lucía
Mayoral Chávez, Miguel Ángel
description Viruses are intracellular pathogens, which are replicated within a cell, using their own machinery to generate more viral particles. Viral replication can affect normal host cell genes, thereby modulating signaling pathways that control cell proliferation, differentiation, and death; genomic integrity, and immune-mediated recognition. Viruses, known as oncogenic viruses, cause about 20% of human cancers. The phenomenon of a basic viral infection to tumorigenesis is long due to the involvement of several factors, such as immune complications, cellular mutations, and exposure to other cancer agents. Epstein-Barr virus (EBV), Kaposi’s sarcoma-associated with herpes, also known as type-8 Herpes virus (HHV-8), human papillomavirus (HPV), hepatitis B virus (HBV), hepatitis C virus (HCV) and type-1 human T-cell lymphotropic virus (HTLV-1) are involved in the development of humans cancers.
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title Los virus como detonante oncogénico
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