Micronutrients- The crucial dietary elements in Covid-19 pandemic: A review

The mutation of the SARS-CoV-2 virus, which cause person-to-person transmission, is the pivotal reason for the pandemic outbreak in the year 2020. Infection symptoms include fever, dry cough, lethargy, severe pneumonia, respiratory distress syndrome, and death. COVID-19 induces a systemic inflammatory reaction that impairs the immune system, commonly known as cytokine release syndrome. Pro-inflammatory cytokines and chemokines are abundant in COVID-19 sufferers' bodies. COVID-19 has a disproportionate impact on the elderly, both directly and through several comorbidities associated with age. Nutrition is without hesitation, a crucial factor in maintaining good health. Some nutrients are essential for the immune system's health and function, exhibiting synergistic actions in critical immune response steps. Vitamin D, C, and Zinc stand out among these nutrients because they have immunomodulatory properties and help to maintain physical tissue barriers. Considering the viability of the virus, nutrients that boost the immunity henceforth the severity of viral infections declines with improved prognosis become important. As a result, the purpose of this review is to provide a complete outline of vitamins D, C, and zinc's involvement during the immune response towards infection, and to enlighten their commensal action of maintaining physical barriers including integument and mucous membrane. Appropriate vitamin D, C, and zinc consumption may represent a feasible pharmacological intervention during the COVID-19 pandemic due to the high surge in population interaction and the commencement of inflammation.