Glomangiopericytoma of the nasal cavity: A case report and review of the literature

Glomangiopericytoma is a rare tumor that represents less than 1% of all sinonasal neoplasms. The clinical and histologic characteristics of glomangiopericytoma, also called sinonasal hemangiopericytoma, differ from those of hemangiopericytoma developing elsewhere in the body. Accordingly, the World Health Organization (WHO) classified this tumor as a distinct entity in 2005. The patient was a 46-year-old man who presented with epistaxis, and was found to have a mass in the right nasal cavity. Computed tomography scan (CT) and magnetic resonance imaging (MRI) revealed the mass filling the right nasal cavity with extension into the adjacent sphenoid sinus, and bilateral neck lymph node swellings. Positron emission tomography/computed tomography scan (PET/CT) showed low accumulation of F-18 labeled 2-fluoro-2-deoxy-D-glucose (18F-FDG) on the tumor. Two years later, he presented to our department with worsening nasal congestion. Endoscopic examination of the nasal cavity and CT revealed enlargement of the tumor, so a complete endoscopic excision of the lesion was performed. Histological examination showed tumor proliferation of spindle-shaped cells and perivascular hyalinization. These histopathologial findings led to a diagnosis of glomangiopericytoma. Eighteen months after the resection, no evidence of recurrence was noted.