Efficacy of Calcitonin Gene-Related Peptide Antagonists in the Treatment of Acute Migraine: A Systematic Review and Meta-analysis

Efficacy of Calcitonin Gene-Related Peptide Antagonists in the Treatment of Acute Migraine: A Systematic Review and Meta-analysis

Objective. This study determined the efficacy of calcitonin gene-related peptide (CGRP) antagonists in the treatment of acute migraine. Methods. Seven randomized, controlled trials were included. Outcome measures used were pain freedom and pain relief two hours after treatment. Results. The differen...

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Veröffentlicht in:Acta medica Philippina 2019-02, Vol.53 (1)
Hauptverfasser: Canlas, Kristina M., Macalintal-Canlas, Regina A., Sakai, Fumihiko
Format: Artikel
Sprache:eng
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Zusammenfassung:Objective. This study determined the efficacy of calcitonin gene-related peptide (CGRP) antagonists in the treatment of acute migraine. Methods. Seven randomized, controlled trials were included. Outcome measures used were pain freedom and pain relief two hours after treatment. Results. The difference in pain freedom 2 hours post-dose significantly favored gepants 140/150 mg (OR=2.39, 95% CI=1.93-2.96, P
ISSN:0001-6071
2094-9278
DOI:10.47895/amp.v53i1.223