Extracellular vesicle-derived microRNA biomarkers: goals and pitfalls

Extracellular vesicle-derived microRNA biomarkers: goals and pitfalls

Liquid biopsy-derived extracellular vesicles (EVs) are an auspicious source for transcriptomic biomarker studies. Here, we review the potential of EV microRNAs (miRNAs) biomarkers, exemplary outline commonly used methods to elucidate new biomarker signatures, and pivotally discuss their applicabilit...

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Veröffentlicht in:Trillium Exctracellular Vesicles 2020-09, Vol.2 (1), p.42-47
Hauptverfasser: Hermann, Stefanie, Grätz, Christian, Kirchner, Benedikt, Pfaffl, Michael W.
Format: Artikel
Sprache:eng
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Zusammenfassung:Liquid biopsy-derived extracellular vesicles (EVs) are an auspicious source for transcriptomic biomarker studies. Here, we review the potential of EV microRNAs (miRNAs) biomarkers, exemplary outline commonly used methods to elucidate new biomarker signatures, and pivotally discuss their applicability at present. Keywords: extracellular vesicles, liquid biopsies, transcriptomic biomarkers, microRNAs
ISSN:2698-8739
DOI:10.47184/tev.2020.01.04