Absolute Concentration Robustness in Rank-One Kinetic Systems

A kinetic system has an absolute concentration robustness (ACR) for a molecular species if its concentration remains the same in every positive steady state of the system. Just recently, a condition that sufficiently guarantees the existence of an ACR in a rank-one mass-action kinetic system was fou...

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Veröffentlicht in:Match (Mülheim) 2024, Vol.91 (2), p.453-483
Hauptverfasser: Mendoza, Eduardo R., Talabis, Dylan Antonio SJ, Jose, Editha C., Fontanil, Lauro L.
Format: Artikel
Sprache:eng
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Zusammenfassung:A kinetic system has an absolute concentration robustness (ACR) for a molecular species if its concentration remains the same in every positive steady state of the system. Just recently, a condition that sufficiently guarantees the existence of an ACR in a rank-one mass-action kinetic system was found. In this paper, it will be shown that this ACR criterion does not extend in general to power-law kinetic systems. Moreover, we also discussed in this paper a necessary condition for ACR in multistationary rank-one kinetic system which can be used in ACR analysis. Finally, a concept of equilibria variation for kinetic systems which are based on the number of the system's ACR species will be introduced here.
ISSN:0340-6253
DOI:10.46793/match.91-2.453M