Vitamin D associated inflammation and atherosclerosis

Vitamin D is known to play a crucial role in mineral homeostasis and bone metabolism. Recent discoveries showed that the vitamin also regulate the inflammatory mediators. A number of studies have reported on the association of low vitamin D levels with increased level of inflammatory parameters; whi...

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Veröffentlicht in:Tropical journal of pharmaceutical research 2021-07, Vol.20 (7), p.1535-1547
Hauptverfasser: Munisamy, Seetha, Mokhtar, Sitisafiah, Hou, Low Jen, Lee, Wee Chee, Rasool, Aida Hanum Ghulam
Format: Artikel
Sprache:eng
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Zusammenfassung:Vitamin D is known to play a crucial role in mineral homeostasis and bone metabolism. Recent discoveries showed that the vitamin also regulate the inflammatory mediators. A number of studies have reported on the association of low vitamin D levels with increased level of inflammatory parameters; which predisposes to atherosclerosis and development of cardiovascular diseases (CVD). Since inflammation is implicated in the pathogenesis of CVD, measurement of inflammatory marker levels has been proposed as a method to improve the prediction of these events. In this review, the mechanism of inflammation and role of vitamin D in combating inflammation are discussed
ISSN:1596-5996
1596-9827
DOI:10.4314/tjpr.v20i7.30