Lipoproetin pattern in patients with chronic renal failure and those who had renal transplantation

Background : Vascular disease is common in patients with chronic renal failure as well as in patients with renal transplantation. It is a common cause of death in these patients. One possible factor for this increased incidence of vascular disease is hyperlipidaemia that frequently occurs in these patients. Purpose : To determine the lipoprotein pattern in patients with chronic renal failure and patients who had renal transplantation in our community. Methods : 70 patients, age ranging between 10-75 years (mean value of 42.7) were studied. They were 21 pre-dialysis patients, 42 dialyzed patients (20 peritoneal dialysis and 22 Haemodialysis, and 15 patients following renal transplantation. Fasting blood Cholesterol, triglyceride, high and low density lipoprotein were determined. Results: 2 patients of the pre-dialysis group had high cholesterol levels, while 6 patients had high triglyceride levels and 7 patients had high serum HDL levels. Only 9 patients had ischaemic changes on E. C. Gs. 3 (7.3 %) patients on dialysis group had high cholesterol levels, 11.9 % had high triglyceride levels. 24 patients of the dialysis group had ischaemic changes in E. C. G. 7 transplant patients had high serum triglyceride levels and only two have elevated LDL.