GENES UNDERLYING POSITIVE INFLUENCE OF PRENATAL ENVIRONMENTAL ENRICHMENT AND NEGATIVE INFLUENCE OF PRENATAL EARTHQUAKE SIMULATION AND CORRECTIVE INFLUENCE OF CHINESE HERBALMEDICINE ON RAT OFFSPRING: IRF7 AND NINJ2

GENES UNDERLYING POSITIVE INFLUENCE OF PRENATAL ENVIRONMENTAL ENRICHMENT AND NEGATIVE INFLUENCE OF PRENATAL EARTHQUAKE SIMULATION AND CORRECTIVE INFLUENCE OF CHINESE HERBALMEDICINE ON RAT OFFSPRING: IRF7 AND NINJ2

Background: Prenatal environmental enrichment (EE) has been proven to positively affect but prenatal stress negatively influence the physiological and psychological processes in animals, whose trans-generational genetic mechanism remains unclearly defined. We aimed to investigate and find out key ge...

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Veröffentlicht in:African journal of traditional, complementary, and alternative medicines complementary, and alternative medicines, 2014-08, Vol.11 (2), p.367
Hauptverfasser: Zhang, Xian Geng, Zhang, Hui, Lin, Lin, Yang, Yi Qing, Deng, Ting Ting, Liu, Qin, Liang, Xiao Li, Wang, Mi Qu, Peng, De Zhong
Format: Artikel
Sprache:eng
Schlagworte:
Earthquake simulation
Irf7
Light Box Defecation Test
Ninj2
Open-field Test
Prenatal stress
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Zusammenfassung:Background: Prenatal environmental enrichment (EE) has been proven to positively affect but prenatal stress negatively influence the physiological and psychological processes in animals, whose trans-generational genetic mechanism remains unclearly defined. We aimed to investigate and find out key genes underlying the positive-negative effects derived from prenatal interventions. Materials and Methods: Pregnant rats were randomized into EE group (EEG), earthquake simulation group (ESG), herbal group (HG) received herbal supplements in feed after earthquake simulation, and control group (CG). Results: Light Box Defecation Test (LBDT) showed EEG offspring presented less fecal pellets than CG offspring, ESG's more than CG's, and HG's less than ESG (p's
ISSN:0189-6016
0189-6016
DOI:10.4314/ajtcam.v11i2.24