Epiretinal membrane formation associated with letrozole therapy – Two case reports

Letrozole, an aromatase inhibitor, is being increasingly used for adjuvant endocrine therapy in hormone-positive postmenopausal breast cancer. Although aromatase inhibitors are thought to increase vitreoretinal traction by causing estrogen reduction, posterior segment complications of letrozole are...

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Veröffentlicht in:Indian journal of ophthalmology - case reports 2024-01, Vol.4 (1), p.159-162
Hauptverfasser: Hareendran, Hridya, Nair, R Unnikrishnan, Soman, Manoj, Vijayan, Varsha
Format: Artikel
Sprache:eng
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Zusammenfassung:Letrozole, an aromatase inhibitor, is being increasingly used for adjuvant endocrine therapy in hormone-positive postmenopausal breast cancer. Although aromatase inhibitors are thought to increase vitreoretinal traction by causing estrogen reduction, posterior segment complications of letrozole are sparsely reported. We report two cases of presumed epiretinal membrane formation in postmenopausal, hormone receptor–positive breast cancer patients on adjuvant letrozole therapy.
ISSN:2772-3070
2772-3089
DOI:10.4103/IJO.IJO_1685_23