The Titration of Scarlatinal Antitoxin in White Pigs

The relative merits and limitations of various methods of titrating scarlet fever antitoxin reported by many authors have been described and discussed in brief. A method of titration of scarlatinal antitoxin with white pigs has been described. This method is not only convenient, but also reasonable since firstly the substance which is responsible for the skin reaction of white pigs was proved to be the essential scarlatinal toxin, and secondly this animal does not react to the nucleoprotein contained in the ordinary Dick toxin which may interfere with the results of the skin test method on human beings.