Motheaten: An Immunodeficient Mouse with Markedly Less Ability to Survive Than the Nude Mouse in a Germfree Environment
The motheaten mouse is an immunodeficient mutant which has been found to have elevated immunoglobulin levels, to exhibit autoimmunity, and early death. Since survival is not improved by a germfree environment, it appears that some mechanism other than infection results in its early demise.
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| Veröffentlicht in: | The Journal of immunology (1950) 1976-05, Vol.116 (5), p.1496-1497 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The motheaten mouse is an immunodeficient mutant which has been found to have elevated immunoglobulin levels, to exhibit autoimmunity, and early death. Since survival is not improved by a germfree environment, it appears that some mechanism other than infection results in its early demise. |
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| ISSN: | 0022-1767 1550-6606 |
| DOI: | 10.4049/jimmunol.116.5.1496 |