Association of the H 2 FPEF Risk Score with Recurrence of Atrial Fibrillation Following Pulmonary Vein Isolation

While atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) commonly coexist, the efficacy of pulmonary vein isolation in the setting of HFpEF is unclear. In a cohort of patients who underwent cryoballoon ablation (CBA) from 2011 to 2016, we calculated the H FPEF risk score, a novel 6-item score (scale: 0-9 points) that accurately predicts the probability of HFpEF. We compared characteristics of patients by H FPEF score and evaluated the association of H FPEF score with 12-month recurrence of AF post-procedure. Of patients with available data to calculate the H FPEF score (n=105), the median H FPEF score was 5 (interquartile range: 4-6), corresponding to >80% probability of HFpEF. Compared to patients with H FPEF scores ≤4 (n=34), patients with H FPEF scores of 5 and 6 (n=46) and ≥7 (n=25) carried higher rates of hypertension (≤4: 21% vs. 5 and 6: 63% vs. ≥7: 88%, P