The regio isomeric effect on the triplet state lifetime of non-peripheral substituted alkylbenzopyridoporphyrazines for photodynamic therapy of cancer

Synthesis of zinc non-peripheral substituted alkylbenzopyridoporphyrazines and separation of their regio isomers have been reported. The triplet state lifetime of zinc non-peripheral substituted alkylbenzopyridoporphyrazines in polymer film was measured by laser flash photolysis in order to estimate an ability to use the sensitizers for photodynamic therapy of cancer. The lowest symmetric isomer of zinc non-peripheral substituted alkylbenzopyridoporphyrazines showed the longest triplet state lifetime.