The therapeutic effect of voglibose for late dumping syndrome in a patient receiving maintenance dialysis was confirmed by continuous glucose monitoring : A case report

A 52-year-old woman had continually felt ill after meals since she had undergone total gastrectomy for gastric cancer 10 years earlier. However, the condition was left untreated. In September 2012, the subject was started on hemodialysis for end-stage renal failure (unknown underlying disease, without diabetes), and she was receiving continuous maintenance dialysis on an outpatient basis at our hospital. In May 2013, the subject went into a hypoglycemic coma after breakfast, which was improved by intravenous glucose infusion. As the subject did not wish to be hospitalized for a detailed examination, she underwent continuous glucose monitoring (CGM) on an outpatient basis. On the basis of postprandial hypoglycemia revealed by CGM and the fact that the subject had undergone gastrectomy, a diagnosis of late dumping syndrome was made. Treatment was initiated with the oral administration of voglibose at a dose of 0.3 mg following breakfast and dinner, and the subjective symptoms and blood glucose fluctuations on CGM improved. We hereby report on this valuable case of late dumping syndrome in a patient receiving hemodialysis in which CGM confirmed the improvement in blood glucose fluctuation by voglibose treatment.