Efficacy of Colestimide as a phosphate binder in patients on chronic hemodialysis

In some patients on chronic hemodialysis, serum phosphorus (P) levels were decreased during administration of Colestimide, a hypercholesterolemia drug that absorbs bile acid. This study investigated the effectiveness of Colestimide as a phosphate binder. Serum P levels were determined before and after treatment with Colestimide for 4 weeks in 31 prospective patients and the results were as follows: 1) There was no difference in serum P levels at 4, 2, and 0 weeks before treatment, but those levels decreased significantly with Colestimide treatment from 6.1±1.1mg/dl to 5.5±1.2, 5.4±1.1 and 5.3±1.2mg/dl at 2, 3 and 4 weeks after treatment (p