Treatment of dialysis-induced hypotension by continuous infusion of Glyceol® with intermittent infusion of 10% NaCl

Three hemodialysis (HD) patients who had frequent dialysis-induced hypotension underwent a continuous infusion of Glyceol® (100ml/hr) combined with intermittent infusions of 10% NaCl (20ml) at the start of HD and at 1, 2 and 3 hrs after the start of HD, to prevent dialysis-induced hypotension. The frequency of dialysis-induced hypotension was significantly decreased in all patients and the predetermined ultrafiltration volume for each patient could be gained. Subsequently, decreases of body weight and of cardiothoracic ratio were recognized after HD in all patients. However, increases of interdialytic body weight and blood pressure before HD probably due to a rise of water intake resulting from thirst, were noted. It is concluded that a continuous infusion of Glyceol® combined with intermittent infusions of 10% NaCl can be effective in preventing dialysis-induced hypotension. However, further studies are required to determine the appropriate doses.