Studies on sequential changes of lipid metabolism in long-term CAPD patients
Sequential changes in serum lipids, apoprotein and post-dextran sulfate lipolytic activity were studied in long-term CAPD patients. Hypertriglyceridemia was temporally accelerated after 7-12 months of CAPD, but this acceleration was gradually corrected by continuation of CAPD over 2 years. HDL-chole...
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| Veröffentlicht in: | Journal of Japanese Society for Dialysis Therapy 1987/10/28, Vol.20(10), pp.765-769 |
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| container_end_page | 769 |
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| container_issue | 10 |
| container_start_page | 765 |
| container_title | Journal of Japanese Society for Dialysis Therapy |
| container_volume | 20 |
| creator | Igaki, Naoya Nishian, Yoshihiko Arakawa, Toshio Matsushita, Kenji Miki, Shozo Goto, Takeo Kawabata, Yoshinori Sakai, Rumi Nishioka, Masatomi Komaba, Keitaro Fujita, Yoshikazu |
| description | Sequential changes in serum lipids, apoprotein and post-dextran sulfate lipolytic activity were studied in long-term CAPD patients. Hypertriglyceridemia was temporally accelerated after 7-12 months of CAPD, but this acceleration was gradually corrected by continuation of CAPD over 2 years. HDL-cholesterol increased slightly after 7-12 months of CAPD, but this was not statistically significant. LCAT activity gradually decreased during long-term CAPD and apo-A1, A2 decreased after 37 months of CAPD. Apo-B and apo-E showed no significant changes during CAPD. The changes in these various parameters were considered responsible for the early development of atherosclerosis. However, it is considered that a less marked change in apo C2/C3 ratio and a slight increase in LPL, HTGL activity as a result of long-term CAPD may protect against atherosclerosis in CAPD patients. Further studies will thus be needed to overcome these problems. |
| doi_str_mv | 10.4009/jsdt1985.20.765 |
| format | Article |
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Hypertriglyceridemia was temporally accelerated after 7-12 months of CAPD, but this acceleration was gradually corrected by continuation of CAPD over 2 years. HDL-cholesterol increased slightly after 7-12 months of CAPD, but this was not statistically significant. LCAT activity gradually decreased during long-term CAPD and apo-A1, A2 decreased after 37 months of CAPD. Apo-B and apo-E showed no significant changes during CAPD. The changes in these various parameters were considered responsible for the early development of atherosclerosis. However, it is considered that a less marked change in apo C2/C3 ratio and a slight increase in LPL, HTGL activity as a result of long-term CAPD may protect against atherosclerosis in CAPD patients. Further studies will thus be needed to overcome these problems.</description><identifier>ISSN: 0911-5889</identifier><identifier>EISSN: 1884-6211</identifier><identifier>DOI: 10.4009/jsdt1985.20.765</identifier><language>jpn</language><publisher>The Japanese Society for Dialysis Therapy</publisher><subject>apoprotein ; atherogenecity ; CAPD ; post dextran sulfate lipolytic activity (PDSLA) ; TG removal capacity</subject><ispartof>Journal of Japanese Society for Dialysis Therapy, 1987/10/28, Vol.20(10), pp.765-769</ispartof><rights>The Japanese Society for Dialysis Therapy</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,4024,27923,27924,27925</link.rule.ids></links><search><creatorcontrib>Igaki, Naoya</creatorcontrib><creatorcontrib>Nishian, Yoshihiko</creatorcontrib><creatorcontrib>Arakawa, Toshio</creatorcontrib><creatorcontrib>Matsushita, Kenji</creatorcontrib><creatorcontrib>Miki, Shozo</creatorcontrib><creatorcontrib>Goto, Takeo</creatorcontrib><creatorcontrib>Kawabata, Yoshinori</creatorcontrib><creatorcontrib>Sakai, Rumi</creatorcontrib><creatorcontrib>Nishioka, Masatomi</creatorcontrib><creatorcontrib>Komaba, Keitaro</creatorcontrib><creatorcontrib>Fujita, Yoshikazu</creatorcontrib><title>Studies on sequential changes of lipid metabolism in long-term CAPD patients</title><title>Journal of Japanese Society for Dialysis Therapy</title><addtitle>Journal of Japanese Society for Dialysis Therapy</addtitle><description>Sequential changes in serum lipids, apoprotein and post-dextran sulfate lipolytic activity were studied in long-term CAPD patients. Hypertriglyceridemia was temporally accelerated after 7-12 months of CAPD, but this acceleration was gradually corrected by continuation of CAPD over 2 years. HDL-cholesterol increased slightly after 7-12 months of CAPD, but this was not statistically significant. LCAT activity gradually decreased during long-term CAPD and apo-A1, A2 decreased after 37 months of CAPD. Apo-B and apo-E showed no significant changes during CAPD. The changes in these various parameters were considered responsible for the early development of atherosclerosis. However, it is considered that a less marked change in apo C2/C3 ratio and a slight increase in LPL, HTGL activity as a result of long-term CAPD may protect against atherosclerosis in CAPD patients. Further studies will thus be needed to overcome these problems.</description><subject>apoprotein</subject><subject>atherogenecity</subject><subject>CAPD</subject><subject>post dextran sulfate lipolytic activity (PDSLA)</subject><subject>TG removal capacity</subject><issn>0911-5889</issn><issn>1884-6211</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><recordid>eNpVkMFKAzEQhoMoWGrPXvMC206yyW5yLNVqoaBg7yGbZGvKbrZu0oNvb0q14GUGhv_7GT6EHgnMGYBcHKJNRAo-pzCvK36DJkQIVlSUkFs0AUlIwYWQ92gWo28AKipkRfkEbT_SyXoX8RBwdF8nF5LXHTafOuzP1xZ3_ugt7l3SzdD52GMfcDeEfZHc2OPV8v0JH3XyGYwP6K7VXXSz3z1Fu_XzbvVabN9eNqvltjCkglCUjmsg1DKgVkvbQkOJJawR1kloDCNW1rU0roXWWsmFyf_XVc2Zq0tCWTlFi0utGYcYR9eq4-h7PX4rAuqsQ_3pUBRU1pGJ9YU4xKT37prXY_Kmc__yueMyM3gNZB-jcqH8AYOqbI4</recordid><startdate>1987</startdate><enddate>1987</enddate><creator>Igaki, Naoya</creator><creator>Nishian, Yoshihiko</creator><creator>Arakawa, Toshio</creator><creator>Matsushita, Kenji</creator><creator>Miki, Shozo</creator><creator>Goto, Takeo</creator><creator>Kawabata, Yoshinori</creator><creator>Sakai, Rumi</creator><creator>Nishioka, Masatomi</creator><creator>Komaba, Keitaro</creator><creator>Fujita, Yoshikazu</creator><general>The Japanese Society for Dialysis Therapy</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>1987</creationdate><title>Studies on sequential changes of lipid metabolism in long-term CAPD patients</title><author>Igaki, Naoya ; Nishian, Yoshihiko ; Arakawa, Toshio ; Matsushita, Kenji ; Miki, Shozo ; Goto, Takeo ; Kawabata, Yoshinori ; Sakai, Rumi ; Nishioka, Masatomi ; Komaba, Keitaro ; Fujita, Yoshikazu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c160n-3e5a012d402da9df0b21d14b8de90bc41d9779cef0fdd958c09176754e731243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>jpn</language><creationdate>1987</creationdate><topic>apoprotein</topic><topic>atherogenecity</topic><topic>CAPD</topic><topic>post dextran sulfate lipolytic activity (PDSLA)</topic><topic>TG removal capacity</topic><toplevel>online_resources</toplevel><creatorcontrib>Igaki, Naoya</creatorcontrib><creatorcontrib>Nishian, Yoshihiko</creatorcontrib><creatorcontrib>Arakawa, Toshio</creatorcontrib><creatorcontrib>Matsushita, Kenji</creatorcontrib><creatorcontrib>Miki, Shozo</creatorcontrib><creatorcontrib>Goto, Takeo</creatorcontrib><creatorcontrib>Kawabata, Yoshinori</creatorcontrib><creatorcontrib>Sakai, Rumi</creatorcontrib><creatorcontrib>Nishioka, Masatomi</creatorcontrib><creatorcontrib>Komaba, Keitaro</creatorcontrib><creatorcontrib>Fujita, Yoshikazu</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of Japanese Society for Dialysis Therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Igaki, Naoya</au><au>Nishian, Yoshihiko</au><au>Arakawa, Toshio</au><au>Matsushita, Kenji</au><au>Miki, Shozo</au><au>Goto, Takeo</au><au>Kawabata, Yoshinori</au><au>Sakai, Rumi</au><au>Nishioka, Masatomi</au><au>Komaba, Keitaro</au><au>Fujita, Yoshikazu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Studies on sequential changes of lipid metabolism in long-term CAPD patients</atitle><jtitle>Journal of Japanese Society for Dialysis Therapy</jtitle><addtitle>Journal of Japanese Society for Dialysis Therapy</addtitle><date>1987</date><risdate>1987</risdate><volume>20</volume><issue>10</issue><spage>765</spage><epage>769</epage><pages>765-769</pages><issn>0911-5889</issn><eissn>1884-6211</eissn><abstract>Sequential changes in serum lipids, apoprotein and post-dextran sulfate lipolytic activity were studied in long-term CAPD patients. Hypertriglyceridemia was temporally accelerated after 7-12 months of CAPD, but this acceleration was gradually corrected by continuation of CAPD over 2 years. HDL-cholesterol increased slightly after 7-12 months of CAPD, but this was not statistically significant. LCAT activity gradually decreased during long-term CAPD and apo-A1, A2 decreased after 37 months of CAPD. Apo-B and apo-E showed no significant changes during CAPD. The changes in these various parameters were considered responsible for the early development of atherosclerosis. However, it is considered that a less marked change in apo C2/C3 ratio and a slight increase in LPL, HTGL activity as a result of long-term CAPD may protect against atherosclerosis in CAPD patients. Further studies will thus be needed to overcome these problems.</abstract><pub>The Japanese Society for Dialysis Therapy</pub><doi>10.4009/jsdt1985.20.765</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0911-5889 |
| ispartof | Journal of Japanese Society for Dialysis Therapy, 1987/10/28, Vol.20(10), pp.765-769 |
| issn | 0911-5889 1884-6211 |
| language | jpn |
| recordid | cdi_crossref_primary_10_4009_jsdt1985_20_765 |
| source | J-STAGE Free |
| subjects | apoprotein atherogenecity CAPD post dextran sulfate lipolytic activity (PDSLA) TG removal capacity |
| title | Studies on sequential changes of lipid metabolism in long-term CAPD patients |
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