A Report of Two Cases of Severe Thrombocytopenia after Hemorrhoidectomy and Fistulectomy

A 35-year-old man underwent hemorrhoidectomy. Four days after the operation, his platelet count had reduced to 0.5×104/μL. We diagnosed drug-induced severe thrombocytopenia and discontinued the medicine that might have been the cause. Transfusions of concentrated platelets were executed, which were effective and his platelet count normalized. A 62-year-old man underwent fistulectomy. Five days after the operation, his platelet count had reduced to 0.8×104/μL. We diagnosed drug-induced severe thrombocytopenia and discontinued the medicine that might have been the cause. Transfusions of concentrated platelets were executed, which were effective and his platelet count normalized. Drug-induced severe thrombocytopenia is rare but is a high-risk factor of postoperative bleeding. We must be careful of drug-induced thrombocytopenia when administering antibiotics and analgesics in hemorrhoidectomy and fistulectomy.