Oncological and surgical characteristics of patients with ovarian cancer diagnosed in the main multidisciplinary hospital in Romania

Malignant ovarian neoplasms represent a public health issue, being one of the most frequent cancers among women, exhibiting the highest mortality rate. The general purpose of this study lays in the analysis of the metastasizing potential of malignant ovarian neoplasms, the correlation between the histological subtype and the genesis of the metastasis. We present an observational retrospective study spanning over 2 years, between 2018-2019, on 30 admitted patients who were treated for malignant ovarian neoplasms in the department of Obstetrics and Gynecology of Bucharest Emergency University Hospital. The most frequent histopathological subtype encountered in our study has been the high grade serous ovarian carcinoma 46,67%, with 30% presenting poorly differentiated neoplasms (G3), therefore having poor prognosis. A considerable number of patients 56,67% presented ascites (among which 43,33% of patients also exhibited peritoneal carcinomatosis, direct dissemination representing the main metastasizing pathway of malignant ovarian neoplasms in the patients included in our study. From our study we can conclude that patients with ovarian malignant neoplasms are diagnosed in an advanced stage of the disease, when metastasis are already present, with a poor prognosis. This is mainly due to the lack of regular gynecological check-ups in menopausal women and because it is considered that once past the fertile age the gynecological examination no longer represents a necessity.