Experimental Study of Effect of Low Power Laser Irradiation on Wound Healing by Difference of Irradiation Method (II)

The author had reported that laser irradiation with energy density 4J/cm2 at every other days was most effective for wound healing. But there is a report which described that laser irradiation with energy density under 4J/cm2 was effective for wound healing too. Then, the effect of irradiation with under 4J/cm2 He-Ne laser on wound healing was studied. Twenty-four wister rats were subjected to this experiment. A open wound, 20mm in diameter as deep as muscle layer were made on the back of anesthetized animals. To find the suitable energy density of laser irradiation, the wound was irradiated with He-Ne laser by energy density of 4J/cm2, 2J/cm2 and 1J/cm2 every other day until the wound completely healed. The wound healing was much more accelerated by irradiation with energy density of 4J/cm2 than the other group. This result suggested that laser irradiation with energy density 4J/cm2 at every other days is most effective for wound healing.