The Role of Pathology and Oncology in the Anatomic-clinical and Biochemical Particulars of the Oral Tumours

Malign tumours of the oral cavity is one of the most frequent types of cancer,1 mostly in developing regions either in the developed world. The Romanian authorities said that the second cause of death in the world is cancer, as it is only overtaken by cardiovascular diseases. Cancer causes more than 6 million deaths per year (O.S.) or more than 10% of all deaths in the world. In Romania, cancer mortality has been around12-15% of the total number of deaths of various causes over the last decade. After the age of 60, almost one in four people died through cancer.Of all cancers, oral cancer accounts for about 4,5% and causes 4,2% of deaths, a percentage that is constantly increasing (PARKIN, STJERNSWARD and MUIR). Oncology is a medical specialty that deals with the diagnosis, treatment and prevention of the disease of human cancer. The oncological examination may suggest the malignant disease (some changes in the history and physical examination of the patient) and the laboratory analysis (markers of tumour) and imaging (mammography, ultrasound, CT, MRI, endoscopy) may bring additional information regarding the presence of the neoplastic process. For the dental pathologyit is indispensable the pathological anatomy for a correct diagnosis and to establish a correct treatment. Although oral cavity is an easily accessible area for clinical examination and more than 80% of the population often benefit from dental examination, a large part of the cancers developing at this level are diagnosed relatively late to sometimes even considerable size when their treatment is already ineffective. The patients presentthemselves very late for dental clinical examination, in most cases without any symptoms because of the character of the disease in the early stages. Finding the early lesions with carcinogen risk save lives and is correlated with decreased range of risks and best prospective results. We ve made this study in the Oral and Maxillo-Facial Surgery Clinic and in the Oncology Clinic in a period of 2 years, between 2017-2019, a number of 146 cases with different oral tumours were solved and followed; of these 49.27% were men and 50.73% women.The age average was between 18-65 years and the highest incidence was between 45-62 years. Systemic treatments were administrated and evaluated in all patients.