Potential biomarkers predictors of mortality in COVID-19 patients in the Emergency Department

Identify which biomarkers performed in the first emergency analysis help to stratify COVID-19 patients according to mortality risk. Observational, descriptive and cross-sectional study performed with data collected from patients with suspected COVID-19 in the Emergency Department from February 24 to...

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Veröffentlicht in:Revista española de quimioterapia 2020-08, Vol.33 (4), p.267-273
Hauptverfasser: Pascual Gómez, N F, Monge Lobo, I, Granero Cremades, I, Figuerola Tejerina, A, Ramasco Rueda, F, von Wernitz Teleki, A, Arrabal Campos, F M, Sanz de Benito, M A
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Sprache:eng ; spa
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Zusammenfassung:Identify which biomarkers performed in the first emergency analysis help to stratify COVID-19 patients according to mortality risk. Observational, descriptive and cross-sectional study performed with data collected from patients with suspected COVID-19 in the Emergency Department from February 24 to March 16, 2020. The univariate and multivariate study was performed to find independent mortality markers and calculate risk by building a severity score. A total of 163 patients were included, of whom 33 died and 29 of them were positive for the COVID-19 PCR test. We obtained as possible factors to conform the Mortality Risk Score age> 75 years ((adjusted OR = 12,347, 95% CI: 4,138-36,845 p = 0.001), total leukocytes> 11,000 cells / mm3 (adjusted OR = 2,649, 95% CI: 0.879-7.981 p = 0.083), glucose> 126 mg / dL (adjusted OR = 3.716, 95% CI: 1.247-11.074 p = 0.018) and creatinine> 1.1 mg / dL (adjusted OR = 2.566, 95% CI: 0.889- 7.403, p = 0.081) This score was called COVEB (COVID, Age, Basic analytical profile) with an AUC 0.874 (95% CI: 0.816-0.933, p
ISSN:0214-3429
1988-9518
DOI:10.37201/req/060.2020