Determining the mean difference in central corneal thickness measured by applanation ultrasound and oculus Wavelight Occulyzer II

Abstract Objective: The objective is to determine the mean difference of central corneal thickness measurements by using ultrasound pachymeter and oculus Wavelight Occulyzer II. Patients & Methods: This prospective cross-sectional comparative study was conducted at Department of Ophthalmology, Liaquat National Hospital, Karachi for 6 months duration, after the approval from ethical committee. Patients were included in our study on the basis of inclusion & exclusion criteria. Central corneal thickness measurements was taken by using ultrasound pachymeter & oculus Wavelight Occulyzer II. All the data was collected by single researcher. The results were plotted, compared & analyzed. Results: 130 patients attending ophthalmology department and fulfilling the inclusion criteria were assessed. One eye of each patient was measured (65 were right eye and 65 were left eye). 73(56.2%) were male and 57(43.8%) were females. Mean age of these patients was 33.9 ±8.9 years. The mean ± SD thinnest oculus Wavelight Occulyzer II measurement was 538.61±23.46 ?m and ranged between 476.0 and 619.0 ?m whereas the mean thinnest ultrasound pachymeter measurement was 535.1±21.816?m and ranged between 482 and 601 ?m. There was highly significant correlation of central corneal thickness between both the instruments. (r=0.96, p