ABCB1 Polymorphism Is Associated with Higher Carbamazepine Clearance in Children

ABCB1 Polymorphism Is Associated with Higher Carbamazepine Clearance in Children

The aim of our study was to investigate the role of ABCB1 polymorphism in the pharmacokinetics of carbamazepine (CBZ) in children. The study enrolled 47 Serbian pediatric epileptic patients on CBZ treatment. Genotyping for ABCB1 1236C

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Veröffentlicht in:Pediatric reports 2025-01, Vol.17 (1), p.10
Hauptverfasser: Djordjevic, Natasa, Cukic, Jelena, Dragas Milovanovic, Dragana, Radovanovic, Marija, Radosavljevic, Ivan, Vuckovic Filipovic, Jelena, Obradovic, Slobodan, Baskic, Dejan, Milovanovic, Jasmina R., Jankovic, Slobodan, Milovanovic, Dragan
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Sprache:eng
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Zusammenfassung:The aim of our study was to investigate the role of ABCB1 polymorphism in the pharmacokinetics of carbamazepine (CBZ) in children. The study enrolled 47 Serbian pediatric epileptic patients on CBZ treatment. Genotyping for ABCB1 1236C
ISSN:2036-7503
2036-7503
DOI:10.3390/pediatric17010010