Biocatalytic Oxidation of Alcohols

Enzymatic methods for the oxidation of alcohols are critically reviewed. Dehydrogenases and oxidases are the most prominent biocatalysts, enabling the selective oxidation of primary alcohols into aldehydes or acids. In the case of secondary alcohols, region and/or enantioselective oxidation is possi...

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Veröffentlicht in:	Catalysts 2020-09, Vol.10 (9), p.952, Article 952
Hauptverfasser:	Puetz, Hendrik, Puch'ova, Eva, Vrankova, Kvetoslava, Hollmann, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol alcohol dehydrogenases alcohol oxidases alcohol oxidation Alcohols Aldehydes Biocatalysts Catalysts Chemical properties Chemical reactions Chemistry Chemistry, Physical Costs Dehydrogenases deracemization Enantiomers Enzymes kinetic resolution Observations Oxidation Oxidation-reduction reactions Oxidoreductases Physical Sciences Proteins Science & Technology
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Beschreibung
Zusammenfassung:	Enzymatic methods for the oxidation of alcohols are critically reviewed. Dehydrogenases and oxidases are the most prominent biocatalysts, enabling the selective oxidation of primary alcohols into aldehydes or acids. In the case of secondary alcohols, region and/or enantioselective oxidation is possible. In this contribution, we outline the current state-of-the-art and discuss current limitations and promising solutions.
ISSN:	2073-4344 2073-4344
DOI:	10.3390/catal10090952