The differences in assessment of the disease activity of atopic dermatitis among physicians and numerical indexes based on blood tests

Atopic dermatitis (AD) is an eczematous disease with repeated exacerbations and remissions. The Severity Scoring of Atopic Dermatitis (SCORAD), a well-known objective assessment index, uses complicated methods. There is reportedly a correlation between the disease activity of AD and serum thymus and...

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Veröffentlicht in:Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology 2014, Vol.28(1), pp.119-125
Hauptverfasser: Koizumi, Munemitsu, Kuzume, Kazuyo
Format: Artikel
Sprache:eng ; jpn
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Zusammenfassung:Atopic dermatitis (AD) is an eczematous disease with repeated exacerbations and remissions. The Severity Scoring of Atopic Dermatitis (SCORAD), a well-known objective assessment index, uses complicated methods. There is reportedly a correlation between the disease activity of AD and serum thymus and activation-regulated chemokine/CCL17 (TARC). We examined the differences in SCORAD results among individual physicians, TARC, immunoglobulin E, eosinophils, and Lactate dehydrogenase in 7 infants with AD. There was variability among the SCORAD results as scored by each physician. There was a tendency for a correlation between TARC and SCORAD results for experienced physicians and a significant correlation for allergists. Serum TARC was considered to contribute meaningfully to AD assessment.
ISSN:0914-2649
1882-2738
DOI:10.3388/jspaci.28.119