Interaction of naturally occurring aflatoxins in poultry feed and immunization against fowl cholera

A total of 1,175 poultry feed samples originating from different farms were analyzed for aflatoxin. Poor growth rate and reduced egg production were the main complaints. The rate of contamination with aflatoxin ranged from 10 to 54% of all samples. Of samples examined 30.7% proved positive for aflatoxin with a concentration ranging from 1 to 2,000 ppb. Outbreaks of fowl cholera were diagnosed on two farms where aflatoxin was detected in the rations used. The impact of aflatoxin in the feed on the efficacy of immunization against fowl cholera was monitored by a hemagglutination test and the titers of the involved farms were compared with experimental groups fed on aflatoxin-free rations and vaccinated with the same polyvalent fowl cholera bacterin. The antibody titers of the experimental groups were 4 to 15 times higher than those of the involved farms.