INCREASE IN THE AMOUNT OF ADSORPTION OF SODIUM CHONDROITIN-6-SULFATE ON HYDROXYAPATITE OWING TO THE VOLUME EFFECT OF POLYMER COIL OF NON-ADSORBABLE POLYMER, POLYVINYLPYRROLIDONE

Sodium chondroitin-6-sulfate (Na2Chs) was adsorbed by hydroxyapatite (HAP), while polyvinylpyrrolidone (PVP) was not. When these polymers were mixed in an aqueous phase, polymer coil of PVP excluded that of Na2Chs, resulting in increases in chemical potential and adsorption amount of Na2Chs. It seemed as if Na2Chs was concentrated by PVP. The concentration effect of non-adsorbable polymer, PVP, on the adsorption amount of Na2Chs was discussed.