Decrease in hepatic storage of vitamin A and induction of cytochrome P-450 by dietary organochlorine pesticides in rats

Decrease in hepatic storage of vitamin A and induction of cytochrome P-450 by dietary organochlorine pesticides in rats

The present experiments were conducted to examine the relation between vitamin A (V. A) storage and cytochrome P-450 (P-450) content in the liver of rats given organochlorine pesticides. Male Sprague Dawley rats (4-week-old) weighing 86g-116g were fed diets containing seven organochlorine pesticides...

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Veröffentlicht in:Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 1991/02/05, Vol.32(1), pp.1-7_1
Hauptverfasser: Ikegami, S. (National Inst. of Health and Nutrition, Tokyo (Japan)), Tsuchihashi, F, Nishide, E
Format: Artikel
Sprache:eng ; jpn
Schlagworte:
A hepatic vitamin A
BHC
CITOCROMO P 450
COMPOSE ORGANOCHLORE
COMPUESTO ORGANICO DEL CLORO
CYTOCHROME P 450
DDT
dieldrin
endrin
FOIE
heptachlor
HIGADO
LIVER
methylcholanthrene
ORGANOCHLORINE COMPOUNDS
organochlorine pesticide
PESTICIDE
PESTICIDES
phenobarbital
PLAGUICIDAS
RAT
RATA
RATS
VITAMINAS
VITAMINE
VITAMINS
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Zusammenfassung:The present experiments were conducted to examine the relation between vitamin A (V. A) storage and cytochrome P-450 (P-450) content in the liver of rats given organochlorine pesticides. Male Sprague Dawley rats (4-week-old) weighing 86g-116g were fed diets containing seven organochlorine pesticides for 2 weeks. A negative correlation (r=-0.766, p
ISSN:0015-6426
1882-1006
DOI:10.3358/shokueishi.32.1